CANNABINOID RECEPTORS

Cannabinoid receptors can be activated by endocannabinoids produced by our body (anandamide and arachidonoylglycerol), synthetic cannabinoids, or plant cannabinoids found in cannabis. Thus, the body perceives plant cannabinoids as its own and does not reject them.

We have CB1 receptors in the central nervous system, connective tissue, glands and gonads, as well as in the cerebral cortex and brain regions such as the hippocampus, basal ganglia, cerebellum and amygdala. CB2 receptors are mostly found in lymphatic organs (spleen, spleen, palate, bone marrow) and white blood cells. Because the receptors are spread over two different areas, they are activated by different types of cannabinoids.

Thus, THC, which also contains psychoactive substances, acts on CB1 receptors and thus works well in all depressive states, Alzheimer’s and Parkinson’s disease, pain, inflammation (arthritis, lupus), hormonal disorders and many forms of cancer. Unlike THC, CBD acts on CB2 receptors and thus helps with all inflammatory bowel diseases such as Crohn’s disease and leaky gut syndrome, and also has many positive effects on all forms of blood disorders and cancer.

Each individual differs in the number of CB1 and CB2 receptors, which determines their response and sensitivity to CBD and THC. In order to achieve the maximum benefit, the ratio of THC to CBD in preparations should vary according to the individual and the number of CB1 and CB2 receptors in his body.

Many researchers believe that CBD is the most important cannabinoid ever discovered, so research and studies are actively continuing, as it shows great therapeutic potential in healthcare, and it can even be said that it is one of the most popular dietary supplements that individuals consume daily . Of course, science has already synthesized pure, synthetic cannabinoids, mainly THC and CBD, which it uses to make some drugs that are already on the market, but experience with the use of synthetic cannabinoids shows that they are significantly less effective than natural forms of cannabinoids.